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Sections for C. Email address. First Name let us know your preferred name. Last Name. Thank you for subscribing Your in-depth digestive health guide will be in your inbox shortly. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry. Request an Appointment at Mayo Clinic. Colon and rectum Open pop-up dialog box Close. Colon and rectum The colon, also called the large intestine, is a long, tube-like organ in your abdomen.
Share on: Facebook Twitter. Show references Clostridioides formerly Clostridium difficile-induced diarrhea. Merck Manual Professional Version. Accessed May 24, LaMont JT. Clostridium difficile in adults: Epidemiology, microbiology, and pathophysiology. Frequently asked questions about Clostridium difficile for healthcare providers.
Centers for Disease Control and Prevention. Guh AY, et al. Trends in U. New England Journal of Medicine. Clostridium difficile in adults: Clinical manifestations and diagnosis. Jameson JL, et al. Clostridium difficile infection, including pseudomembranous colitis. In: Harrison's Principles of Internal Medicine.
New York, N. McDonald LC, et al. Clinical Infectious Diseases. Clostridium difficile infection adult. Rochester, Minn. Kelly CP, et al. Clostridium difficile in adults: Treatment. However, other bacteria that live in the intestines usually keep the amount of C. Symptoms of a C. You should also seek immediate treatment if you have severe abdominal pain or notice blood in your stool. The C. You can develop an infection if you touch a contaminated surface and then touch your mouth.
In addition, the spores of C. As a result, they can stick around for a long time. To diagnose a C. Next, they may order a stool sample. They can analyze it for toxins or toxin genes of the C. If your symptoms are severe, they may also perform a procedure called a sigmoidoscopy. A long, thin device called a sigmoidoscope is inserted into your colon. This allows your doctor to get a better look at your colon and check for signs of inflammation.
Oral fidaxomicin and oral vancomycin are both first-line treatment options for C. Oral metronidazole is less effective and is used as a suggested alternative treatment for a nonsevere initial C.
In most cases, you can take the antibiotics by mouth, which is the standard therapy for the three options noted above. However, some infections might require intravenous IV antibiotic therapy.
In the case of someone with recurrent C. As you recover, make sure to drink plenty of fluids. In more severe cases, you may need intravenous fluid to treat dehydration as well. While most C. Call them if your symptoms return after treatment finishes, as it may need to be repeated. The bacteria often live harmlessly because other bacteria normally found in the bowel keep it under control. But some antibiotics can interfere with the balance of bacteria in the bowel, which can cause the C.
When this happens, C. Once out of the body, the bacteria turn into resistant cells called spores. These can survive for long periods on hands, surfaces such as toilets , objects and clothing unless they're thoroughly cleaned, and can infect someone else if they get into their mouth. Someone with a C. You can reduce your risk of picking it up or spreading it by practising good hygiene, both at home and in healthcare settings.
Find out how to prevent germs spreading. Page last reviewed: 23 November Next review due: 23 November Clostridium difficile. Symptoms of a Clostridium difficile C.
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